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Serious side effects of Tramadol Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following: Ø   Serotonin syndrome. ·          fast heart rate ·          high blood pressure ·          body temperature that’s higher than normal ·          reflexes that are stronger than normal ·          lack of coordination (control of your movements) ·          nausea and vomiting ·          diarrhea ·          agitation ·          hallucinations (seeing or hearing things that aren’t real) ·          coma Ø   Serious breathing problems.  ·         slowed breathing rate ·         very shallow breathing (little chest movement with breathing) ·         fainting, dizziness, or confusion Ø   Physical dependence and withdrawal when stopping the drug. ·         feeling irritable, anxious, or restless

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